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Forgetting to remove air bubbles can lead to discomfort during injection

Phase II clinical trials for inflammatory bowel disease reported no toxicity or adverse events in treated patients, though detailed safety data from these trials have not been published in peer-reviewed literature

10.1002/mnfr.201900045 405 SeyfriedT

Gills et al

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The phase 2b ENLIVEN trial, a multicenter, randomized, double-blind, placebo-controlled study, included 222 patients with biopsy-confirmed NASH and F2-F3 fibrosis, assigned to receive pegozafermin at doses of 15 mg weekly, 30 mg weekly, 44 mg every 2 weeks, or placebo for 24 weeks